Regional variation in use of exogenous and endogenous glomerular filtration rate (GFR) markers in Sweden

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Regional variation in use of exogenous and endogenous glomerular filtration rate (GFR) markers in Sweden

BACKGROUND Markers of renal function (glomerular filtration rate (GFR)) are frequently used in the Swedish health care. GFR is usually estimated based on plasma creatinine concentration, but plasma cystatin C concentration, creatinine clearance, iohexol clearance, and (51)Cr-EDTA clearance are also used. These markers are all part of the daily patient care, but there is little specific informat...

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SERUM CYSTATIN C AS A NEW MARKER OF GLOMERULAR FILTRATION RATE (GFR)

Cystatin C is a 13 KD basic protein that is a member of the cystatin superfamily of cysteine protease inhibitors. The cystatin C gene seems to be a house keeping gene, which is compatible with a stable production rate of cystatin C by most cells. This protein is freely filtered through the glomerulus and almost completely reabsorbed and catabolized by proximal tubular cells. Because of the...

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Exogenous Fluorescent Agents for the Determination of Glomerular Filtration Rate

Glomerular filtration rate (GFR) is now widely accepted as the best indicator of renal function in the state of health and illness.1,2 Current clinical guidelines advocate its use in the staging of chronic kidney disease as well as in assessing the risk of kidney failure under acute clinical, physiological, and pathological conditions.3-6 Acute renal failure (ARF) is a major cause of complicati...

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ژورنال

عنوان ژورنال: Upsala Journal of Medical Sciences

سال: 2012

ISSN: 0300-9734,2000-1967

DOI: 10.3109/03009734.2012.664179